20080911

Neonatal lupus erythematosus (NLE)

Neonatal lupus erythematosus (NLE) is a misnomer, as these newborns do not have systemic lupus erythematosus, but a constellation of clinical disorders associated with, and probably in part caused by, autoantibodies that are passively acquired by the fetus transplacentally.

The majority of newborns with NLE exhibit cutaneous or cardiac disease, among other symptoms.

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