Carbicarb is referred to as a "CO2 -consuming" buffer, which is a misnomer because it still generates CO2 , but less than NaHCO3 of equal effectiveness. Carbicarb increases P CO2 less and decreases intracellular pH less than an equimolar treatment with NaHCO3 alone.
This could be valuable in a clinical setting of compromised CO2 elimination. Despite the theoretic advantage, Carbicarb has not been shown to be superior to NaHCO3 in treatment of lactic acidosis.
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