NonSpecific or Solitary Rectal or Colon Ulcer

Nonspecifc ulceration of the colon and rectum is a clinical entity characterized by ulceration in various segments of the large intestine and rectum.

The common term “solitary ulceration” is a misnomer, as ulcers may be multiple. Rectal ulcers account for 5% of solitary ulcers, with the remainder occurring in the cecum (45%), ascending colon (20%), and sigmoid (16%).

Three distinct syndromes are seen:

Nonspecific colonic ulcers,

Dieulafoy-type ulcer, and

Solitary rectal ulcer syndrome.